25 years ago today (5/8/01), David Byrne released one of his most adventurous and eclectic solo albums, Look Into the Eyeball, his sixth studio LP. Backed by 49 musicians across 12 genre-hopping tracks, Byrne effortlessly moves from the infectious pop of “Like Humans Do” to the Spanish-language duet “Desconocido Soy” featuring Café Tacvba vocalist Nrü. Equal parts quirky, sophisticated, and globally inspired, Look Into the Eyeball remains one of Byrne’s boldest post-Talking Heads statements. Watch Byrne and many musicians perform “The Great Intoxication” live on Conan O’Brien in 2001